Methotrexate is a folic acid antagonist that was originally approved to treat a variety of cancers. Used for oncologic indications, methotrexate is administered in cyclical frequencies and in variable doses based on body surface area and the type of cancer being treated—for example, 12 g/m 2 per...
Resource Library
Whether you have experienced a medication error in your organization or you are proactively implementing prevention strategies, you are not alone. Thousands of organizations worldwide have relied on ISMP's resources for institutional change to reduce errors on a daily basis. These resources are developed from ISMP's review of reports through its national error reporting programs, peer-reviewed articles in its publications, and/or consensus gathering summits on topics pertinent to specific errors or hazards. ISMP offers a wide range of downloadable and easy to use resources. Many are free.
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Students Have a Key Role in a Culture of Safety: Analysis of Student-Associated Medication Incidents
Undergraduate and postgraduate students in healthcare fields are attempting to develop the skills required to deliver safe and effective patient care as future practitioners. As part of their training, most students are exposed to a variety of practice environments and direct patient care...
Between November 2017 and March 2018, ISMP conducted three surveys to learn about current practices with smart infusion pumps that have dose error-reduction software (DERS). Smart pumps can vastly improve medication safety by providing customizable libraries with dose limits and administration rates...
Vaccination ranks high among the greatest public health achievements of the twentieth century. However, analysis of 575 vaccine errors submitted to the ISMP National Vaccine Errors Reporting Program (ISMP VERP) in 2017, which appeared in our June 14, 2018 newsletter ( Part I ), suggests that vaccine...
Vaccine errors threaten to undermine the protection immunizations provide and often leave patients inadequately protected against serious diseases
Hospira, a Pfizer company, released a letter last week, in coordination with the US Food and Drug Administration (FDA), detailing instructions for handling certain drugs and lot numbers of CARPUJECT glass syringes that may have cracked needle hubs and/or contain particulate matter. The list includes...
Problem: Earlier this month, ISMP held its second national summit on smart infusion pumps. The first summit, held in 2008, examined smart pump implementation, drug libraries, and clinical practice, and resulted in publication of the ISMP Guidelines for Safe Implementation and Use of Smart Infusion...
The latest issue of ISMP’s QuarterWatch™ (see description at the end of the article) examines drug safety issues identified by monitoring new adverse drug event reports submitted to the US Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS). New data received during the third...
Limited regulatory guidance exists for investigational drug labeling, packaging, and nomenclature, exposing sites that participate in clinical trials to many troubling product-related safety risks. Many of these risks are unique to investigational drugs and are less likely to be encountered with US...