|
Medication Orders
Each order represents a hazard alert or an adverse event
published in the ISMP Medication Safety Alert!,
and most have led to (or could cause) serious patient
harm, sometimes death.
|
Test Patient Parameters
(if applicable)
|
Unsafe Order Detected
|
Able to Override Warning
|
Able to Override Warning if Reason
Noted
|
|
Yes
|
No
|
Yes
|
No
|
Yes
|
No
|
| 1. methotrexate 7.5 mg PO daily |
Rheumatoid arthritis |
29%
|
71%
|
87%
|
13%
|
77%
|
23%
|
| 2. Wellbutrin XL 300 mg PO daily |
Seizure disorder |
19%
|
81%
|
83%
|
17%
|
84%
|
16%
|
| 3. Percocet (any strength) PO q4h prn |
Also: Tylenol 650 mg PO q4h prn |
73%
|
27%
|
91%
|
9%
|
85%
|
15%
|
| 4. Fluzone 0.5 mL IM |
Allergy to eggs |
44%
|
56%
|
85%
|
15%
|
79%
|
21%
|
| 5. Zyban 150 mg PO BID |
Also: Wellbutrin SR 150 mg PO BID |
82%
|
18%
|
96%
|
4%
|
81%
|
19%
|
| 6. Lovenox 60 mg subcutaneously q12h |
Also: heparin 1,000 units/hour IV |
85%
|
15%
|
94%
|
6%
|
85%
|
15%
|
| 7. Sporanox 100 mg PO daily |
Congestive heart failure |
14%
|
86%
|
89%
|
11%
|
85%
|
15%
|
| 8. St. John's Wort 300 mg PO TID |
indinavir 800 mg PO q8h |
25%
|
75%
|
83%
|
17%
|
77%
|
23%
|
| 9. Varivax 0.5 mL subcutaneously |
Female; pregnant |
19%
|
81%
|
88%
|
12%
|
74%
|
26%
|
| 10. metformin 500 mg PO BID |
Serum creatinine: 2.1 mg/dL |
45%
|
55%
|
88%
|
12%
|
79%
|
21%
|
| 11. Neutra-Phos-K 2 packets PO TID |
Potassium: 6.1 mEq/L |
32%
|
68%
|
89%
|
11%
|
76%
|
24%
|
| 12. rifampin 600 mg PO daily |
Also: saquinavir 1,200 mg PO TID |
75%
|
25%
|
92%
|
8%
|
91%
|
9%
|
| 13. lomustine 190 mg PO daily for 6 weeks |
Body surface area: 1.46 m2 |
24%
|
76%
|
75%
|
25%
|
72%
|
28%
|
| 14. carbamazepine 400 mg PO BID |
4-year-old child |
33%
|
67%
|
90%
|
10%
|
76%
|
24%
|
| 15. carbamazepine 1,300 mg PO BID |
No specific parameters |
46%
|
54%
|
88%
|
13%
|
76%
|
24%
|
| 16. Lantus 25 units IV now |
Diabetes |
30%
|
70%
|
62%
|
38%
|
52%
|
48%
|
| 17. vincristine 2 mg intrathecally today |
Acute leukemia |
36%
|
64%
|
61%
|
39%
|
46%
|
54%
|
| 18. amphotericin B 260 mg IV daily |
No specific parameters |
43%
|
57%
|
88%
|
12%
|
78%
|
22%
|