Results for ISMP Survey on High-Alert Medications

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Total: 1170

Medication or Class of Medications

Unless otherwise stated, the intended use for all medications is pediatric and adult patients.

Section A

Do YOU believe this is a high-alert medication?

Section B

Does YOUR PRACTICE SITE consider this a high-alert medication with special precautions in place?

Class/Category of Medications Yes No Yes No
1. IV adrenergic agonists (e.g., epinephrine) 82% 18% 70% 30%
2. IV adrenergic antagonists (e.g., propranolol) 72% 28% 63% 37%
3. Parenteral chemotherapeutic agents 99% 1% 95% 5%
4. Oral chemotherapeutic agents 85% 15% 78% 22%
5. Neuromuscular blocking agents (e.g., succinylcholine) 96% 4% 88% 13%
6. IV thrombolytics/fibrinolytics (e.g., tenecteplase) 90% 10% 80% 20%
7. Liposomal forms of drugs (e.g., amphotericin B) 70% 30% 60% 40%
8. Glycoprotein IIb/IIIa inhibitors (e.g., tirofiban) 80% 20% 71% 29%
9. IV conscious sedation agents (e.g., midazolam) 86% 14% 81% 19%
10. Oral conscious sedation agents for children (e.g., chloral hydrate) 64% 36% 53% 47%
11. Oral/IM narcotics/opiates 56% 44% 68% 32%
12. IV narcotics/opiates 85% 15% 79% 21%
13. Dialysate 66% 34% 62% 38%
14. Cardioplegic solutions 81% 19% 73% 27%
15. Total parenteral nutrition 76% 24% 75% 25%
16. Inhaled and IV general anesthetic agents (e.g., propofol) 87% 13% 78% 22%
17. IV inotropic medications (e.g., digoxin, milrinone) 81% 19% 70% 30%
18. Benzodiazepines in patients over 65 (e.g., alprazolam) 70% 30% 62% 38%
19. Oral hypoglycemic agents (e.g., glipizide) 58% 42% 54% 46%
20. Low molecular weight heparin 72% 28% 66% 34%
Specific Medications Yes No Yes No
22. Warfarin 85% 15% 74% 26%
23. IV heparin 93% 7% 89% 11%
24. Subcutaneous insulin 84% 16% 78% 22%
25. IV insulin 94% 6% 88% 12%
26. IV magnesium sulfate 83% 17% 77% 23%
27. IV calcium gluconate 78% 22% 73% 27%
28. IV calcium chloride 81% 19% 74% 26%
29. IV potassium phosphate 94% 6% 88% 12%
30. IV potassium chloride 98% 2% 95% 5%
31. Hypertonic sodium chloride injection 95% 5% 87% 13%
32. High concentration dextrose injection 76% 24% 70% 30%
33. IV theophylline 73% 27% 66% 34%


Total for Nurse: 99

Medication or Class of Medications

Unless otherwise stated, the intended use for all medications is pediatric and adult patients.

Section A

Do YOU believe this is a high-alert medication?

Section B

Does YOUR PRACTICE SITE consider this a high-alert medication with special precautions in place?

Class/Category of Medications Yes No Yes No
1. IV adrenergic agonists (e.g., epinephrine) 95% 5% 78% 22%
2. IV adrenergic antagonists (e.g., propranolol) 89% 11% 74% 26%
3. Parenteral chemotherapeutic agents 98% 2% 90% 10%
4. Oral chemotherapeutic agents 84% 16% 80% 20%
5. Neuromuscular blocking agents (e.g., succinylcholine) 95% 5% 80% 20%
6. IV thrombolytics/fibrinolytics (e.g., tenecteplase) 92% 8% 84% 16%
7. Liposomal forms of drugs (e.g., amphotericin B) 82% 18% 71% 29%
8. Glycoprotein IIb/IIIa inhibitors (e.g., tirofiban) 87% 13% 76% 24%
9. IV conscious sedation agents (e.g., midazolam) 92% 8% 88% 12%
10. Oral conscious sedation agents for children (e.g., chloral hydrate) 73% 27% 65% 35%
11. Oral/IM narcotics/opiates 66% 34% 80% 20%
12. IV narcotics/opiates 90% 10% 84% 16%
13. Dialysate 82% 18% 82% 18%
14. Cardioplegic solutions 93% 7% 88% 12%
15. Total parenteral nutrition 80% 20% 81% 19%
16. Inhaled and IV general anesthetic agents (e.g., propofol) 93% 7% 83% 17%
17. IV inotropic medications (e.g., digoxin, milrinone) 87% 13% 82% 18%
18. Benzodiazepines in patients over 65 (e.g., alprazolam) 84% 16% 76% 24%
19. Oral hypoglycemic agents (e.g., glipizide) 61% 39% 66% 34%
20. Low molecular weight heparin 69% 31% 66% 34%
Specific Medications Yes No Yes No
22. Warfarin 75% 25% 72% 28%
23. IV heparin 89% 11% 88% 12%
24. Subcutaneous insulin 78% 22% 77% 23%
25. IV insulin 95% 5% 90% 10%
26. IV magnesium sulfate 86% 14% 79% 21%
27. IV calcium gluconate 87% 13% 79% 21%
28. IV calcium chloride 87% 13% 78% 22%
29. IV potassium phosphate 93% 7% 85% 15%
30. IV potassium chloride 95% 5% 87% 13%
31. Hypertonic sodium chloride injection 85% 15% 76% 24%
32. High concentration dextrose injection 78% 22% 74% 26%
33. IV theophylline 81% 19% 76% 24%


Total for Pharmacist: 795

Medication or Class of Medications

Unless otherwise stated, the intended use for all medications is pediatric and adult patients.

Section A

Do YOU believe this is a high-alert medication?

Section B

Does YOUR PRACTICE SITE consider this a high-alert medication with special precautions in place?

Class/Category of Medications Yes No Yes No
1. IV adrenergic agonists (e.g., epinephrine) 69% 31% 50% 50%
2. IV adrenergic antagonists (e.g., propranolol) 52% 48% 38% 62%
3. Parenteral chemotherapeutic agents 100% 0% 94% 6%
4. Oral chemotherapeutic agents 76% 24% 64% 36%
5. Neuromuscular blocking agents (e.g., succinylcholine) 96% 4% 84% 16%
6. IV thrombolytics/fibrinolytics (e.g., tenecteplase) 85% 15% 68% 32%
7. Liposomal forms of drugs (e.g., amphotericin B) 49% 51% 33% 67%
8. Glycoprotein IIb/IIIa inhibitors (e.g., tirofiban) 69% 31% 53% 47%
9. IV conscious sedation agents (e.g., midazolam) 77% 23% 68% 32%
10. Oral conscious sedation agents for children (e.g., chloral hydrate) 64% 36% 43% 57%
11. Oral/IM narcotics/opiates 47% 53% 42% 58%
12. IV narcotics/opiates 75% 25% 63% 37%
13. Dialysate 40% 60% 30% 70%
14. Cardioplegic solutions 66% 34% 50% 51%
15. Total parenteral nutrition 65% 35% 61% 39%
16. Inhaled and IV general anesthetic agents (e.g., propofol) 79% 21% 64% 36%
17. IV inotropic medications (e.g., digoxin, milrinone) 70% 30% 50% 50%
18. Benzodiazepines in patients over 65 (e.g., alprazolam) 50% 50% 36% 64%
19. Oral hypoglycemic agents (e.g., glipizide) 34% 66% 24% 76%
20. Low molecular weight heparin 56% 44% 44% 56%
Specific Medications Yes No Yes No
22. Warfarin 79% 21% 60% 40%
23. IV heparin 91% 9% 85% 15%
24. Subcutaneous insulin 77% 23% 66% 34%
25. IV insulin 92% 8% 81% 19%
26. IV magnesium sulfate 73% 27% 65% 35%
27. IV calcium gluconate 63% 37% 56% 44%
28. IV calcium chloride 69% 31% 59% 41%
29. IV potassium phosphate 92% 8% 85% 15%
30. IV potassium chloride 98% 2% 96% 4%
31. Hypertonic sodium chloride injection 95% 5% 83% 17%
32. High concentration dextrose injection 63% 37% 52% 48%
33. IV theophylline 55% 45% 41% 59%


Total for Other: 276

Medication or Class of Medications

Unless otherwise stated, the intended use for all medications is pediatric and adult patients.

Section A

Do YOU believe this is a high-alert medication?

Section B

Does YOUR PRACTICE SITE consider this a high-alert medication with special precautions in place?

Class/Category of Medications Yes No Yes No
1. IV adrenergic agonists (e.g., epinephrine) 92% 8% 88% 12%
2. IV adrenergic antagonists (e.g., propranolol) 88% 12% 84% 16%
3. Parenteral chemotherapeutic agents 98% 2% 97% 3%
4. Oral chemotherapeutic agents 95% 5% 92% 8%
5. Neuromuscular blocking agents (e.g., succinylcholine) 97% 3% 93% 7%
6. IV thrombolytics/fibrinolytics (e.g., tenecteplase) 93% 7% 91% 9%
7. Liposomal forms of drugs (e.g., amphotericin B) 87% 13% 82% 18%
8. Glycoprotein IIb/IIIa inhibitors (e.g., tirofiban) 89% 11% 87% 13%
9. IV conscious sedation agents (e.g., midazolam) 92% 8% 92% 8%
10. Oral conscious sedation agents for children (e.g., chloral hydrate) 60% 40% 58% 42%
11. Oral/IM narcotics/opiates 60% 40% 89% 11%
12. IV narcotics/opiates 94% 6% 92% 8%
13. Dialysate 85% 15% 84% 16%
14. Cardioplegic solutions 90% 10% 88% 12%
15. Total parenteral nutrition 86% 14% 87% 13%
16. Inhaled and IV general anesthetic agents (e.g., propofol) 93% 7% 90% 10%
17. IV inotropic medications (e.g., digoxin, milrinone) 92% 8% 86% 14%
18. Benzodiazepines in patients over 65 (e.g., alprazolam) 87% 13% 84% 16%
19. Oral hypoglycemic agents (e.g., glipizide) 82% 18% 80% 20%
20. Low molecular weight heparin 90% 10% 88% 12%
Specific Medications Yes No Yes No
22. Warfarin 95% 5% 90% 10%
23. IV heparin 96% 4% 94% 6%
24. Subcutaneous insulin 93% 7% 91% 9%
25. IV insulin 97% 3% 95% 5%
26. IV magnesium sulfate 92% 8% 89% 11%
27. IV calcium gluconate 91% 9% 88% 12%
28. IV calcium chloride 91% 9% 88% 13%
29. IV potassium phosphate 97% 3% 93% 7%
30. IV potassium chloride 98% 2% 96% 4%
31. Hypertonic sodium chloride injection 98% 2% 94% 6%
32. High concentration dextrose injection 90% 10% 87% 13%
33. IV theophylline 88% 12% 87% 13%

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