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Interim instructions for flushing the filter and line following administration of SPORANOX (itraconazole) Injection until defective two-way stop-cock assembly is corrected.

From the March 22, 2000 issue

Instructions for "Preparing the admixture," noted in our last issue, remain unchanged. After infusing 60 mL of the drug, discontinue the infusion. DO NOT FLUSH VIA THE SIDE PORT OF THE 2-WAY STOPCOCK. To properly flush the line, turn the stopcock to the "OFF" position while keeping the side port capped. (The stopcock is in the "OFF" position when the word "OFF" is pointing down.) Disconnect the extension line from the filter set and discard the extension line. (The extension line is the tubing connecting the infusion bag to the filter set.) Connect the apparatus (i.e. syringe) you use to flush the filter set to the top port of the 2-way stopcock. Return the stopcock to the open position. (The stopcock is in the open position when the word "OFF" is pointing left or pointing to the side port.) Via the top port (from which the extension line was removed), flush the line with 15-20 mL of 0.9% Sodium Chloride Injection, USP, over 30 seconds to 15 minutes. After flushing, remove and discard the filter set. For additional information, contact the Medical Information Group in Clinical Affairs at Ortho Biotech at (800) 325-7504, prompt #2.

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